The effects of pulsed electromagnetic field therapy on muscle strength and pain in patients with end-stage knee osteoarthritis: a randomized controlled trial
作者：Qianwen Wang, Michael Tim‐Yun Ong, Gene Chi Wai Man, Alfredo Franco‐Obregón, Ben Chi-yin Choi, Pauline Po Yee Lui, Daniel Tik-Pui Fong, Jihong Qiu, Xin He, Jonathan Patrick Ng, Patrick Shu‐Hang Yung · 发表于：Frontiers in Medicine · 年份：2024 · DOI：10.3389/fmed.2024.1435277 · 被引用次数：9 · 研究领域：Electromagnetic Fields and Biological Effects、Magnetic and Electromagnetic Effects、Biofield Effects and Biophysics
Background Osteoarthritis (OA) of the knee is one of the most common chronic degenerative joint conditions affecting aging population. Aim To investigate the effectiveness of a combination of home-based exercise and pulsed electromagnetic field (PEMF) therapy to improve muscle strength, physical function, and pain. Methods Sixty patients were randomly assigned to either home-based exercise alone (control group; n = 30) or combined with PEMF therapy (treatment group; n = 30) twice a week for eight weeks. Knee extension, flexion muscle strength, gait speed (GS), 5 time sit-to-stand test (5STS), Visual Analogue Scale (VAS) pain and Knee Injury and Osteoarthritis Outcome Score (KOOS) were recorded at baseline and 4 and 8 weeks. Results Significant improvements in symptomatic knee extension muscle strength (SKE, p = 0.001), flexion strength (SKF, p = 0.011), contralateral knee extension muscle strength (CKE, p = 0.002), and flexion strength (CKF, p = 0.009) were observed for the PEMF treatment group at 8 weeks. Significant reductions in VAS pain scores were observed in both the treatment ( p < 0.001, partial η 2 = 0.505) and control ( p < 0.001, partial η 2 = 0.268) groups. Significant differences were reported between groups in the 4 ( p = 0.010, partial η 2 = 0.111) and 8 ( p = 0.046, partial η 2 = 0.068) week assessment in VAS pain. A significant time difference was found in GS and 5STS between baseline and week 8 (GS: difference 0.051, p = 0.026; 5STS: difference...