Enhancing Drug Solubility, Bioavailability, and Targeted Therapeutic Applications through Magnetic Nanoparticles

作者：Yue Zhuo, Yong‐Gang Zhao, Yun Zhang · 发表于：Molecules · 年份：2024 · DOI：10.3390/molecules29204854 · 被引用次数：158 · 研究领域：Nanoparticle-Based Drug Delivery、Nanomaterials for catalytic reactions、Graphene and Nanomaterials Applications

Biological variability poses significant challenges in the development of effective therapeutics, particularly when it comes to drug solubility and bioavailability. Poor solubility across varying physiological conditions often leads to reduced absorption and inconsistent therapeutic outcomes. This review examines how nanotechnology, especially through the use of nanomaterials and magnetic nanoparticles, offers innovative solutions to enhance drug solubility and bioavailability. This comprehensive review focuses on recent advancements and approaches in nanotechnology. We highlight both the successes and remaining challenges in this field, emphasizing the role of continued innovation. Future research should prioritize developing universal therapeutic solutions, conducting interdisciplinary research, and leveraging personalized nanomedicine to address biological variability.