Negative 18F-FDG and Positive 68Ga-FAPI-04 Findings in a Patient With Acute Exacerbation of Chronic Cholecystitis

作者：Na Qi, Jie Ding, Haiyan Wang, Jun Zhao · 发表于：Clinical Nuclear Medicine · 年份：2024 · DOI：10.1097/rlu.0000000000005504 · 被引用次数：6 · 研究领域：Peptidase Inhibition and Analysis、Cardiac Structural Anomalies and Repair、Protease and Inhibitor Mechanisms

ABSTRACT: Acute cholecystitis typically exhibits intense FDG uptake of the gallbladder wall. Radiolabeled fibroblast activation protein inhibitor (FAPI) is considered as a potential alternative agent for tumor-specific imaging. We report 18 F-FDG and 68 Ga-FAPI-04 PET/MR findings in a 44-year-old woman with acute exacerbation of chronic cholecystitis. The lesions show negative 18 F-FDG uptake but intense 68 Ga-FAPI-04 uptake in PET/MR. This case highlights the imperative for nuclear medicine clinicians to exercise vigilance when evaluating gallbladder lesions exhibiting intense 68 Ga-FAPI-04 but negative 18 F-FDG uptake.