Prevalence and co‐occurrence of symptoms of mental and substance use disorders among people with HIV age 40 and older in low‐ and middle‐income countries: a cross‐sectional study

作者：Angela M. Parcesepe, Melissa A. Stockton, Charlotte Bernard, Tukiya Kanguya, Edith Kwobah, Álvaro López-Íñiguez, Gad Murenzi, Jeremy Ross, Albert Minga, Fernanda Maruri, Mpho Tlali, Suzanne Goodrich, Hugo Perazzo, Françoise Musabyimana, Smita Nimkar, Kathryn E. Lancaster · 发表于：Journal of the International AIDS Society · 年份：2024 · DOI：10.1002/jia2.26359 · 被引用次数：6 · 研究领域：HIV/AIDS Research and Interventions、HIV-related health complications and treatments、Family Caregiving in Mental Illness

INTRODUCTION: Due to the increased effectiveness of and access to antiretroviral therapy (ART), people with HIV (PWH) are living longer. As a result, the population of older PWH has increased. Mental and substance use disorders (MSDs) are common and frequently co-occurring among PWH and are associated with poor HIV care outcomes. Research into the prevalence and co-occurrence of MSDs among ageing PWH remains limited, particularly in low- and middle-income countries (LMICs). METHODS: We analysed data collected between 2020 and 2022 from the International epidemiology Databases to Evaluate AIDS (IeDEA) Sentinel Research Network cohort of PWH aged 40 years or older on ART at 11 HIV clinics in Brazil, Côte d'Ivoire, India, Kenya, Mexico, Uganda, Rwanda, Togo, Vietnam, Zambia and Zimbabwe. We estimated the prevalence and co-occurrence of unhealthy alcohol use (AUDIT-C ≥3 for women, ≥4 for men), unhealthy drug use (ASSIST >3 for cannabis, cocaine, amphetamines, inhalants, sedatives, hallucinogens and/or opioids), and moderate to severe symptoms of depression (PHQ-9 ≥10), anxiety (GAD-7 ≥10) and post-traumatic stress disorder (PTSD) (PCL-5 ≥33). Psychiatric multimorbidity was defined as having symptoms of two or more disorders assessed. Log binomial models assessed the association between socio-demographic and HIV care characteristics and symptoms of anxiety, depression, PTSD or unhealthy substance use. RESULTS: Of 2821 participants, the prevalence of unhealthy alcohol and drug use ...