Concurrent Intracranial and Spinal Dural Metastases Demonstrated by 68Ga-DOTATATE PET/CT With Negative 123I-MIBG SPECT/CT in a Pediatric Neuroblastoma Patient

作者：Haizhou Qiao, Siqi Li, Yanfeng Xu, Wei Wang, Jigang Yang · 发表于：Clinical Nuclear Medicine · 年份：2024 · DOI：10.1097/rlu.0000000000005448 · 被引用次数：16 · 研究领域：Neuroblastoma Research and Treatments、Glioma Diagnosis and Treatment、Medical Imaging Techniques and Applications

ABSTRACT: Contrast enhancement MRI of the brain and spine showed abnormal enhancement in intracranial and spinal dural lesions in a 6-year-old boy with high-risk neuroblastoma, suggesting the possibility of dural metastases. 123 I-MIBG SPECT/CT did not show any abnormal MIBG accumulation in these lesions. However, 68 Ga-DOTATATE PET/CT showed obvious DOTATATE uptake in these metastatic lesions. Surgical pathology confirmed the diagnosis of intracranial dural metastasis. Concurrent intracranial and spinal dural metastases from neuroblastoma demonstrated by 68 Ga-DOTATATE PET/CT with negative 123 I-MIBG SPECT/CT have not been reported previously.