Absolute coronary flow and microvascular resistance before and after transcatheter aortic valve implantation

作者：Emanuele Gallinoro, Pasquale Paolisso, Dario Tino Bertolone, Giuseppe Esposito, Marta Belmonte, Attilio Leone, Michele Mattia Viscusi, Monika Shumkova, Cristina De Colle, Ivan Degrieck, Filip P A Casselman, Martin Pěnička, Carlos Adolfo Collet, Jeroen Sonck, Eric Wyffels, Jozef Bartunek, Bernard De Bruyne, Marc Vanderheyden, Emanuele Barbato · 发表于：EuroIntervention · 年份：2024 · DOI：10.4244/eij-d-24-00075 · 被引用次数：12 · 研究领域：Cardiac Valve Diseases and Treatments、Cardiovascular Function and Risk Factors、Cardiac Imaging and Diagnostics

BACKGROUND: Severe aortic stenosis (AS) is associated with left ventricular (LV) remodelling, likely causing alterations in coronary blood flow and microvascular resistance. AIMS: We aimed to evaluate changes in absolute coronary flow and microvascular resistance in patients with AS undergoing transcatheter aortic valve implantation (TAVI). METHODS: ) was calculated by dividing absolute flow by the subtended myocardial mass. RESULTS: : 0.34 [IQR 0.30-0.48] vs 0.47 [IQR 0.36-0.67] mL/min/g; p=0.06). CONCLUSIONS: Immediately after TAVI, no changes occurred in absolute coronary flow or coronary flow reserve. Over time, the remodelling of the left ventricle is associated with increased hyperaemic perfusion.