Using priorities between human and livestock bacterial antimicrobial resistance (AMR) to identify data gaps in livestock AMR surveillance

作者：Narmada Venkateswaran, Lucien R Swetschinski, Christina Fastl, Carlotta Di Bari, Nicola G. Criscuolo, Ranya Mulchandani, Cheng Zhao, Tomislav Meštrović, Kevin S Ikuta, Sara Babo Martins, Lucy Coyne, João Sucena Afonso, Ben Huntington, Jonathan Rushton, Brecht Devleesschauwer, Benn Sartorius, Thomas P. Van Boeckel, David M. Pigott · 发表于：BMC Infectious Diseases · 年份：2024 · DOI：10.1186/s12879-024-09847-3 · 被引用次数：8 · 研究领域：Pharmaceutical and Antibiotic Environmental Impacts、Antibiotic Use and Resistance、Salmonella and Campylobacter epidemiology

BACKGROUND: Bacterial antimicrobial resistance (AMR) is a global threat to both humans and livestock. Despite this, there is limited global consensus on data-informed, priority areas for intervention in both sectors. We compare current livestock AMR data collection efforts with other variables pertinent to human and livestock AMR to identify critical data gaps and mutual priorities. METHODS: We globally synthesized livestock AMR data from open-source surveillance reports and point prevalence surveys stratified for six pathogens (Escherichia coli, Staphylococcus aureus, non-typhoidal Salmonella, Campylobacter spp., Enterococcus faecalis, Enterococcus faecium) and eleven antimicrobial classes important in human and veterinary use, published between 2000 and 2020. We also included all livestock species represented in the data: cattle, chickens, pigs, sheep, turkeys, ducks, horses, buffaloes, and goats. We compared this data with intended priorities calculated from: disability-adjusted life years (DALYs), livestock antimicrobial usage (AMU), livestock biomass, and a global correlation exercise between livestock and human proportion of resistant isolates. RESULTS: Resistance to fluoroquinolones and macrolides in Staphylococcus aureus were identified as priorities in many countries but, less than 10% of these reported livestock AMR data. Resistance data for Escherichia coli specific to cattle, chickens, and pigs, which we prioritized, were also well collected. AMR data collection o...