Directions for analgesic development

作者：Ting Ge, Wu Zhou, Sha Sha, Xin Yang, He Liu, Lingzhen Song, Hongxing Zhang · 发表于：Journal of Anesthesia and Translational Medicine · 年份：2024 · DOI：10.1016/j.jatmed.2024.08.003 · 被引用次数：8 · 研究领域：Pediatric Pain Management Techniques、Pain Mechanisms and Treatments、Pain Management and Placebo Effect

Physiological pain represents a protective response to avoid further injury and is helpful for survival. However, pathological pain is a common disease/symptom significantly affecting the quality of daily life in affected patients. Great progress has been made recently in understanding of pain mechanisms and the development of analgesic drugs, yet analgesic development requires continuous innovation. This review aims to summarize potential directions for future analgesic development and to provide guidance for related mechanism studies.