Enhanced Ca2+-Driven Arrhythmogenic Events in Female Patients With Atrial Fibrillation

作者：Xianwei Zhang, Yixuan Wu, Charlotte Smith, William E. Louch, Stefano Morotti, Dobromir Dobrev, Eleonora Grandi, Haibo Ni · 发表于：JACC. Clinical electrophysiology · 年份：2024 · DOI：10.1016/j.jacep.2024.07.020 · 被引用次数：13 · 研究领域：Cardiac electrophysiology and arrhythmias、Cardiovascular Effects of Exercise、Atrial Fibrillation Management and Outcomes

BACKGROUND: Substantial sex-based differences have been reported in atrial fibrillation (AF), but the underlying mechanisms are poorly understood. OBJECTIVES: -targeted interventions. METHODS: -targeted interventions were evaluated. RESULTS: -driven arrhythmogenic events in women, and revealed enhanced efficacy when applied in combination. CONCLUSIONS: -targeted interventions are promising therapeutic approaches in women.