Multidimensional profiling of human T cells reveals high CD38 expression, marking recent thymic emigrants and age-related naive T cell remodeling

作者：Pavla Boháčová, Marina Terekhova, Petr Tsurinov, Riley Mullins, Kamila Husarcikova, Irina Shchukina, Alina Ulezko Antonova, Barbora Echalar, Jan Kössl, Adam Saidu, Thomas Francis, Chelsea Mannie, Laura Arthur, Stephen D. R. Harridge, Daniel Kreisel, Philip A. Mudd, Angela M. Taylor, Coleen A. McNamara, Marina Cella, Sidharth V. Puram, Theo van den Broek, Femke van Wijk, Pirooz Eghtesady, Maxim N. Artyomov · 发表于：Immunity · 年份：2024 · DOI：10.1016/j.immuni.2024.08.019 · 被引用次数：51 · 研究领域：Immune Cell Function and Interaction、T-cell and B-cell Immunology、Cytomegalovirus and herpesvirus research

cells. Identification of RTEs enables direct assessment of thymic health. Furthermore, resolving the dynamics of naive T cell remodeling yields insight into vaccination and infection responsiveness throughout aging.