Evaluation of glycyrrhetinic acid in attenuating adverse effects of a high-fat diet in largemouth bass (Micropterus salmoides)

作者：Quanquan Cao, Zhihao Zhang, Zhao Ju, Lin Feng, Wei‐Dan Jiang, Pei Wu, Juan Zhao, Haifeng Liu, Jiang Jun · 发表于：Animal nutrition · 年份：2024 · DOI：10.1016/j.aninu.2024.09.002 · 被引用次数：15 · 研究领域：Pharmacological Effects of Natural Compounds、Ginseng Biological Effects and Applications、Chromatography in Natural Products

< 0.05). Finally, dietary GA supplementation alleviated mitochondrial damage and reduced reactive oxygen species (ROS) production induced by the HFD. It is concluded that GA supplementation in HFD enhances growth performance, increases mRNA expression and protein levels of tight junction-related parameters, decreases mRNA expression and protein levels of pyroptosis-related genes, and alleviates intestinal mitochondrial injury and inflammation induced by HFD.