Perceived Chronic Traumatic Encephalopathy and Suicidality in Former Professional Football Players

作者：Rachel Grashow, Douglas P. Terry, Grant L. Iverson, Heather DiGregorio, Inana Dairi, Cheyenne Brown, Paula S. Atkeson, Alicia J. Whittington, Le'Roy E. Reese, Jonathan H. Kim, Niki A. Konstantinides, Herman A. Taylor, Frank E. Speizer, Daniel H. Daneshvar, Ross Zafonte, Marc G. Weisskopf, Aaron L. Baggish · 发表于：JAMA Neurology · 年份：2024 · DOI：10.1001/jamaneurol.2024.3083 · 被引用次数：28 · 研究领域：Traumatic Brain Injury Research、Sport Psychology and Performance、Posttraumatic Stress Disorder Research

Importance: Participation in American-style football (ASF) has been linked to chronic traumatic encephalopathy neuropathological change (CTE-NC), a specific neuropathologic finding that can only be established at autopsy. Despite being a postmortem diagnosis, living former ASF players may perceive themselves to have CTE-NC. At present, the proportion and clinical correlates of living former professional ASF athletes with perceived CTE who report suicidality are unknown. Objective: To determine the proportion, clinical correlates, and suicidality of living former professional ASF players with perceived CTE. Design, Setting, and Participants: A cross-sectional study within the Football Players Health Study at Harvard University was conducted from 2017 to 2020. Using electronic and paper surveys, this population-based study included former ASF players who contracted with a professional league from 1960 to 2020 and volunteered to fill out a baseline survey. Data for this study were analyzed from June 2023 through March 2024. Exposures: Data included demographics, football-related exposures (eg, position, career duration), and current health problems (anxiety, attention-deficit/hyperactivity disorder, depression, diabetes, emotional and behavioral dyscontrol symptoms, headache, hyperlipidemia, hypertension, low testosterone level, pain, sleep apnea, and subjective cognitive function). Main Outcomes and Measures: The proportion of participants reporting perceived CTE. Univariable a...