NOP2-mediated 5-methylcytosine modification of APOL1 messenger RNA activates PI3K-Akt and facilitates clear cell renal cell carcinoma progression

作者：Junjie Tian, Jianguo Gao, Cheng Cheng, Zhijie Xu, Xiaoyi Chen, Yunfei Wu, Guanghou Fu, Baiye Jin · 发表于：International Journal of Biological Sciences · 年份：2024 · DOI：10.7150/ijbs.97503 · 被引用次数：17 · 研究领域：Renal and related cancers、Acute Lymphoblastic Leukemia research、Renal Diseases and Glomerulopathies

C-dependent stabilization of APOL1, which in turn regulates the PI3K-Akt signaling pathway, suggesting a potential therapeutic target for ccRCC.