Quantitative Electroencephalography for Predication of Neurological Dysfunction in Type A Aortic Dissection: A Prospective Observational Study

作者：Y. Wang, Yong‐qing Cheng, Hanghang Wang, Hanghang Wang, Huanhuan Wang, Huanhuan Wang, Wenxue Liu, Yi Jiang, Y. Xue, Yang Chen, Qing Zhou, Xuan Luo, Qingxiu Zhang, Jason Zhensheng Qu, Dongjin Wang · 发表于：Journal of the American Heart Association · 年份：2024 · DOI：10.1161/jaha.124.034351 · 被引用次数：6 · 研究领域：Aortic Disease and Treatment Approaches、Congenital Heart Disease Studies、Cardiac and Coronary Surgery Techniques

Background Type A aortic dissection presents challenges with postoperative cerebral complications, and this study evaluates the predictive value of quantitative electroencephalography for perioperative brain function prognosis. Methods and Results Amplitude‐integrated electroencephalography (aEEG) processes raw signals through filtering, amplitude integration, and time compression, displaying the data in a semilogarithmic format. Using this method, postoperative relative band power (post‐RBP) α% and dynamic aEEG (ΔaEEG) grade were significantly associated with neurological dysfunction in univariate and multivariable analyses, with area under the receiver operating characteristic curve of 0.876 (95% CI, 0.825–0.926) for the combined model. Postoperative relative band power α% and ΔaEEG were significantly associated with adverse outcomes, with area under the receiver operating characteristic curve of 0.903 (95% CI, 0.835–0.971) for the combined model. Postoperative relative band power α% and ΔaEEG were significantly associated with transient neurological dysfunction and stroke, with areas under the receiver operating characteristic curve of 0.818 (95% CI, 0.760–0.876) and 0.868 (95% CI, 0.810–0.926) for transient neurological dysfunction, and 0.815 (95% CI, 0.743–0.886) and 0.831 (95% CI, 0.746–0.916) for stroke. Among 56 patients, the Alberta Stroke Program Early Computed Tomography score was superior to ΔaEEG in predicting neurological outcomes (area under the receiver operat...