Millmerranones G, a meroterpene isolated from a mangrove-derived fungus Aspergillus sp. GXIMD 03004

作者：Guang-Ping Cao, Guoqiang Huang, Guang‐Ying Chen, Xiang‐Xi Yi, Xue-Sheng Wang, Feng-Jiao Wei, Cai-Qiong Zhu, Cheng‐Hai Gao, Yong-Hong Liu, Meng Bai · 发表于：Natural Product Research · 年份：2024 · DOI：10.1080/14786419.2024.2402460 · 被引用次数：1 · 研究领域：Microbial Natural Products and Biosynthesis、Marine Sponges and Natural Products、Seaweed-derived Bioactive Compounds

One new meroterpene derivative, millmerranones G (1), and three known analogues (2–4) were identified from the mangrove-derived fungus Aspergillus sp. GXIMD 03004, which was isolated from the leaves of mangrove Acanthus ilicifolius L. collected from Beibu Gulf in China. The structure of 1 was characterised by a comprehensive interpretation of the NMR spectroscopic and HRESIMS data. The absolute configuration for 1 was established using experimental and calculated ECD data. The anti-Vibrio activities of all compounds were evaluated, the result showed that compounds 1 and 2 has weak activity against Vibrio harveyi.