An Analysis of Ultraviolet-C Light Irradiation in Reducing Bacterial Contamination of the Anesthesia Work Area

作者：Stephanie Gibbons, Franklin Dexter, Randy W. Loftus, Carmen T Brindeiro, Kaitlin M. Walker, Michelle C. Parra, Debra J. Szeluga, Melinda Seering, Brent Hadder, Chase P. Loftus, Jonathan E. Charnin · 发表于：Anesthesiology · 年份：2024 · DOI：10.1097/aln.0000000000005128 · 被引用次数：8 · 研究领域：Anesthesia and Sedative Agents、Photoacoustic and Ultrasonic Imaging、Optical Imaging and Spectroscopy Techniques

To the Editor: Surgical site infections are associated with increased patient morbidity and mortality.1 At the University of Iowa (Iowa City, Iowa) and Georgetown University (Washington, D.C.), there were surgical site infections for 12% (13 of 106) with Staphylococcus aureus transmission detected among anesthesia workspace reservoirs versus 2% (8 of 406) without.2 The anesthesia machine is a potent transmission vehicle for more pathogenic strain characteristics such as S. aureus sequence type 5.3 Ultraviolet-C irradiation may help to reduce environmental contamination of the anesthesia work space.4 Important considerations include distance of the environmental surface and/or equipment from the emitters, orientation of the target surface(s), a clinically relevant log reduction, target pathogen(s), and a minimal effective dose to reduce photo reactivation and dark repair.5 While a clinically relevant cleaning threshold for the anesthesia workspace is less than 100 colony-forming units,6 a ultraviolet-C irradiation dose and configuration effective in reducing contamination below this threshold has not been established. We aimed to address these limitations. A linear configuration of three ultraviolet-C irradiation emitters (Surfacide, USA; Fig. S1, https://links.lww.com/ALN/D612) positioned side by side, each rotating 5°, was deployed for direct irradiation of S. aureus American Type Culture Collection 6538 carriers and radiometers positioned at three locations (left, center, a...