Oral Cavity Cancer Secondary to Dental Trauma: A Scoping Review

作者：Carlos M. Chiesa‐Estomba, Miguel Mayo‐Yáñez, Luigi Angelo Vaira, Antonino Maniaci, Allen L. Feng, Maria Landa-Garmendia, Adrian Cardin-Pereda, Jérôme R. Lechien · 发表于：Biomedicines · 年份：2024 · DOI：10.3390/biomedicines12092024 · 被引用次数：12 · 研究领域：Head and Neck Cancer Studies、Oral Health Pathology and Treatment、Oral health in cancer treatment

(1) Background: Oral cavity cancer represents the most common site of origin of head and neck mucosal malignancies. A few limited studies have suggested that chronic irritation, particularly in non-healing ulcers, and fibrotic tissue from poor dentition or ill-fitting dentures had a role in developing mouth cancer. This scoping review aims to evaluate the existing evidence concerning Oral Cavicty Cancer (OCC) in non-smokers/non-drinkers and the relationship with dental trauma. (2) Methods: A scoping review of the PubMed, Embase, and Web of Science databases was completed in adherence with the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews checklist. (3) Results: Of the 33 articles that met inclusion, in 6 of them authors discussed the role of topography in dental trauma, in 11 articles authors discussed the carcinogenesis mechanism involved in chronic mucosal trauma, in 17 articles data on ill-fitting dentures was included, 4 studies dealt with the effect of broken/sharp teeth on mucosal damage, and in 7 studies the role of oral hygiene was covered. Less frequently discussed topics included gender, risk of neck nodes, and the role of potentially malignant oral disorders. (4) Conclusions: The available literature suggests a potential connection between chronic dental trauma and the development of OCC. Studies have highlighted factors such as denture use and ill-fitting dental appliances as contributors to an increased risk of o...