Trends and insights in dengue virus research globally: a bibliometric analysis (1995–2023)

作者：Yumeng Liu, Mengmeng Wang, Ning Yu, Wenxin Zhao, Peng Wang, He Zhang, Wenchao Sun, Ningyi Jin, Huijun Lu · 发表于：Journal of Translational Medicine · 年份：2024 · DOI：10.1186/s12967-024-05561-5 · 被引用次数：22 · 研究领域：Mosquito-borne diseases and control、Academic Publishing and Open Access、Viral Infections and Outbreaks Research

BACKGROUND: Dengue virus (DENV) is the most widespread arbovirus. The World Health Organization (WHO) declared dengue one of the top 10 global health threats in 2019. However, it has been underrepresented in bibliometric analyses. This study employs bibliometric analysis to identify research hotspots and trends, offering a comprehensive overview of the current research dynamics in this field. RESULTS: We present a report spanning from 1995 to 2023 that provides a unique longitudinal analysis of Dengue virus (DENV) research, revealing significant trends and shifts not extensively covered in previous literature. A total of 10,767 DENV-related documents were considered, with a notable increase in publications, peaking at 747 articles in 2021. Plos Neglected Tropical Diseases has become the leading journal in Dengue virus research, publishing 791 articles in this field-the highest number recorded. Our bibliometric analysis provides a comprehensive mapping of DENV research across multiple dimensions, including vector ecology, virology, and emerging therapies. The study delineates a complex network of immune response genes, including IFNA1, DDX58, IFNB1, STAT1, IRF3, and NFKB1, highlighting significant trends and emerging themes, particularly the impacts of climate change and new outbreaks on disease transmission. Our findings detail the progress and current status of key vaccine candidates, including the licensed Dengvaxia, newer vaccines such as Qdenga and TV003, and updated clin...