Prevalence and correlations of schistosomiasis mansoni and schistosomiasis haematobium among humans and intermediate snail hosts: a systematic review and meta-analysis

作者：Xinyao Wang, Qin Li, Yinlong Li, Suying Guo, Shi‐Zhu Li, Xiao‐Nong Zhou, Jiagang Guo, Robert Bergquist, Saleh Juma, Jianfeng Zhang, Kun Yang, Jing Xu · 发表于：Infectious Diseases of Poverty · 年份：2024 · DOI：10.1186/s40249-024-01233-0 · 被引用次数：21 · 研究领域：Parasites and Host Interactions、Parasite Biology and Host Interactions、Helminth infection and control

Abstract Background The control of schistosomiasis is particularly difficult in sub-Saharan Africa, which currently harbours 95% of this disease. The target population for preventive chemotherapy (PC) is expanded to all age group at risk of infection, thus increasing the demands of praziquantel (PZQ) tablets according to the new released guideline by World Health Organization. Due to the gap between available PZQ for PC and requirements, alternative approaches to assess endemicity of schistosomiasis in a community, are urgently needed for more quick and precise methods. We aimed to find out to which degree the infection status of snails can be used to guide chemotherapy against schistosomiasis. Methods We searched literature published from January 1991 to December 2022, that reported on the prevalence rates of Schistosoma mansoni , S. haematobium in the intermediate snails Biomphalaria spp. and Bulinus spp., respectively, and in humans. A random effect model for meta-analyses was used to calculate the pooled prevalence estimate (PPE), with heterogeneity assessed using I-squared statistic ( I 2 ), with correlation and regression analysis for the exploration of the relationship between human S. mansoni and S. haematobium infections and that in their specific intermediate hosts. Results Forty-seven publications comprising 59 field investigations were included. The pooled PPE of schistosomiasis, schistosomiasis mansoni and schistosomiasis haematobium in humans were 27.5% [95% con...