Burden of schistosomiasis in global, regional, and national 1990–2019: A systematic analysis for the Global Burden of Disease Study 2019

作者：Ying Zhang, Yingzi Ming · 发表于：Travel Medicine and Infectious Disease · 年份：2024 · DOI：10.1016/j.tmaid.2024.102751 · 被引用次数：15 · 研究领域：Parasites and Host Interactions、Zoonotic diseases and public health、Research on Leishmaniasis Studies

BACKGROUND: Despite the gradual decline of schistosomiasis due to the efforts of the WHO and various countries, with the WHO setting a goal to eliminate schistosomiasis by 2030, a comprehensive global assessment of the current status of schistosomiasis has not been conducted. OBJECTIVES: To provide a detailed description of the changes in schistosomiasis from 1990 to 2019 by using the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 database. METHODS: We obtained all relevant data on schistosomiasis worldwide from the Global Burden of Diseases (GBD) database from 1990 to 2019. The mortality, prevalence, disability-adjusted life-years (DALYs), Years of Life Lost (YLLs), Years Lived with Disability (YLDs) of schistosomiasis were examined by Socio-demographic Index (SDI), age, sex, and year at the global, region and national level. RESULTS: From 1990 to 2019, the age-standardized rate(ASR)-prevalence of schistosomiasis has decreased from 2600.9 per 100,000(95% uncertainty interval (UI) 2191.2 to 3059.3) to 1805.0 per 100,000(95% UI 1503.4 to 2146.9). The estimated annual percentage change (EAPC) from 1990 to 2019 was 1.28 (95% UI 1.22 to 1.33) in high SDI regions and -2.45 (95% UI -3.03 to -1.86) in low SDI regions. In North Africa and the Middle East, the most substantial reduction in DALYs occurred, with an observed EAPC of -5.36. CONCLUSION: The burden of schistosomiasis has decreased over the past three decades worldwide. However, the high SDI regions h...