Effects of wheat-based fermented liquid feed on growth performance, nutrient digestibility, gut microbiota, intestinal morphology, and barrier function in grower–finisher pigs

作者：Aoran Zhang, Yanyi Yang, Yongli Li, Yunfan Zheng, Hongmei Wang, Hongxiao Cui, Wang Yin, Mei Lv, Yunxiang Liang, Wenli Chen · 发表于：Journal of Animal Science · 年份：2024 · DOI：10.1093/jas/skae229 · 被引用次数：16 · 研究领域：Gut microbiota and health

Fermented liquid feed (FLF) can improve dietary nutrient absorption levels, degrade antinutrient factors in diets, and increase beneficial bacteria abundance in animal guts. However, few systematic studies have been conducted on wheat-based fermented liquid feed (WFLF) in pigs. The present study evaluates the effects of WFLF on the growth performance, nutrient digestibility, gastric volume, intestinal morphology, intestinal health, intestinal barrier function, serum biochemical immunity, gut microbiota, and intestinal microbial diversity of grower-finisher pigs. In total, 80 weaned pigs were randomly allocated to two treatment groups based on their initial body weight: a basal diet with pellet dry feeding (CON) and a basal diet with WFLF, with four replicate pens per group. The experiment lasted 82 d. Compared with CON pigs, those fed WFLF were significantly heavier at 60 to 82 d and had significantly higher average daily feed intake, average daily gain, and gain: feed ratio at 60 to 82 d and 1 to 82 d. WFLF pigs had significantly greater jejunum, total tract, and ileal digestibility for all nutrients and amino acids, excluding arginine, than CON pigs. WFLF intake influenced villus height, villus height:crypt depth ratio of the anterior segment of the jejunum (A-jejunum), crypt depth, and redox potential of the posterior segment of the jejunum (P-jejunum) while significantly affecting body weight. Additionally, FLF improved gastric capacity significantly. Furthermore, mRNA ex...