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Single-cell multi-omics identify novel regulators required for osteoclastogenesis during aging

作者:Hao Li, Wanxing Xu, Jing-Cong Tan, Yue-Mei Hong, Jian He, Ben-Peng Zhao, Jin‐An Zhou, Yu-Min Zheng, Ming Lei, Xiaoqi Zheng, Jun Ding, Ningning Liu, Junjie Gao, Changqing Zhang, Hui Wang · 发表于:iScience · 年份:2024 · DOI:10.1016/j.isci.2024.110734 · 被引用次数:8 · 研究领域:Bone Metabolism and Diseases、Immune cells in cancer、Cytokine Signaling Pathways and Interactions

to play crucial roles. By thoroughly examining the cellular dynamics underpinning bone aging, our study unveils novel insights into the mechanisms of age-related osteoporosis and presents potential therapeutic targets for future exploration.