Artemisinin and Its Derivatives as Potential Anticancer Agents

作者：Luan Wen, Ben Chung-Lap Chan, Ming‐Hua Qiu, Ping‐Chung Leung, Chun Kwok Wong · 发表于：Molecules · 年份：2024 · DOI：10.3390/molecules29163886 · 被引用次数：64 · 研究领域：Malaria Research and Control、Drug-Induced Hepatotoxicity and Protection、Beetle Biology and Toxicology Studies

). Artemisinin and its derivatives share an unusual endoperoxide bridge and are extensively used for malaria treatment worldwide. In addition to antimalarial activities, artemisinin and its derivatives have been reported to exhibit promising anticancer effects in recent decades. In this review, we focused on the research progress of artemisinin and its derivatives with potential anticancer activities. The pharmacological effects, potential mechanisms, and clinical trials in cancer therapy of artemisinin and its derivatives were discussed. This review may facilitate the future exploration of artemisinin and its derivatives as effective anticancer agents.