QRS detection in single-lead, telehealth electrocardiogram signals: Benchmarking open-source algorithms

作者：Florian Kristof, Maximilian Kapsecker, Leon Nissen, James Brimicombe, Martín Cowie, Zixuan Ding, Andrew Dymond, Stephan Jonas, Hannah Clair Lindén, Gregory Y.H. Lip, Kate Williams, Jonathan Mant, Peter Charlton, on behalf of the SAFER Investigators · 发表于：PLOS Digital Health · 年份：2024 · DOI：10.1371/journal.pdig.0000538 · 被引用次数：11 · 研究领域：ECG Monitoring and Analysis、Cardiac electrophysiology and arrhythmias、Atrial Fibrillation Management and Outcomes

BACKGROUND AND OBJECTIVES: A key step in electrocardiogram (ECG) analysis is the detection of QRS complexes, particularly for arrhythmia detection. Telehealth ECGs present a new challenge for automated analysis as they are noisier than traditional clinical ECGs. The aim of this study was to identify the best-performing open-source QRS detector for use with telehealth ECGs. METHODS: The performance of 18 open-source QRS detectors was assessed on six datasets. These included four datasets of ECGs collected under supervision, and two datasets of telehealth ECGs collected without clinical supervision. The telehealth ECGs, consisting of single-lead ECGs recorded between the hands, included a novel dataset of 479 ECGs collected in the SAFER study of screening for atrial fibrillation (AF). Performance was assessed against manual annotations. RESULTS: A total of 12 QRS detectors performed well on ECGs collected under clinical supervision (F1 score ≥0.96). However, fewer performed well on telehealth ECGs: five performed well on the TELE ECG Database; six performed well on high-quality SAFER data; and performance was poorer on low-quality SAFER data (three QRS detectors achieved F1 of 0.78-0.84). The presence of AF had little impact on performance. CONCLUSIONS: The Neurokit and University of New South Wales QRS detectors performed best in this study. These performed sufficiently well on high-quality telehealth ECGs, but not on low-quality ECGs. This demonstrates the need to handle low-...