Syntheses and biological activities of calix[4]resorcinarene derivatives modified by sulfonic acid and sulfonamides

作者：Xiaodan Ye, Qing Wang, Meng Sun, Lusi Chen, Ai‐Quan Jia, Qian‐Feng Zhang · 发表于：RSC Advances · 年份：2024 · DOI：10.1039/d4ra04426f · 被引用次数：8 · 研究领域：Molecular Sensors and Ion Detection、Supramolecular Chemistry and Complexes、Marine Toxins and Detection Methods

. In terms of antitumor activity, calix[4]resorcinarenes and their derivatives showed inhibitory effects on the three tumor cells selected for the experiment. Among them, the survival rate of A549 was 76.03% in the presence of 40 μM 1b, and the survival rates of HepG2 and MDA-MB-321 were 28.66% and 65.39% in the presence of 40 μM 2b, respectively.