SUMO E3 ligase MUL1 inhibits lymph node metastasis of bladder cancer by mediating mitochondrial HSPA9 translocation

作者：Jilin Wu, Ming Huang, Wentao Dong, Yuelong Chen, Qianghua Zhou, Qiang Zhang, Junjiong Zheng, Yeqing Liu, Yangjie Zhang, Sen Liu, Chenwei Yang, Siting Chen, Jian Huang, Tianxin Lin, Xu Chen · 发表于：International Journal of Biological Sciences · 年份：2024 · DOI：10.7150/ijbs.98772 · 被引用次数：15 · 研究领域：Ubiquitin and proteasome pathways、Bladder and Urothelial Cancer Treatments、Histone Deacetylase Inhibitors Research

assays revealed that MUL1 inhibits the metastasis and proliferation of BCa cells. Overall, our study reveals a novel function and molecular mechanism of SUMO E3 ligases in LN metastasis.