Association between excessive alcohol consumption and incident diabetes mellitus among Japanese based on propensity score matching

作者：Changchun Cao, Cuimei Wei, Yong Han, Jiao Luo, Ping Xi, Jingying Chen, Xiaohua Xiao, Haofei Hu, Dongli Qi · 发表于：Scientific Reports · 年份：2024 · DOI：10.1038/s41598-024-68202-3 · 被引用次数：15 · 研究领域：Alcohol Consumption and Health Effects、Substance Abuse Treatment and Outcomes、Diabetes, Cardiovascular Risks, and Lipoproteins

The available evidence on the connection between excessive alcohol consumption and diabetes is controversial. Therefore, the primary objective of this investigation was to examine the connection between excessive alcohol consumption and incident diabetes in a Japanese population through the utilization of propensity score matching (PSM) analysis. Our retrospective cohort study encompassed a sample of 15,464 Japanese individuals who were initially free of diabetes between the years 2004 and 2015. The study utilized comprehensive medical records of individuals who underwent a physical examination. Employing a one:one PSM analysis, the current research included 2298 individuals with and without excessive alcohol consumption. Furthermore, a doubly robust estimation method was employed to ascertain the connection between excessive alcohol consumption and diabetes. The findings revealed that individuals with excessive alcohol consumption exhibited a 73% higher likelihood of developing diabetes (HR = 1.73, 95% CI 1.08-2.77). Furthermore, upon adjusting for variables, the PSM cohort demonstrated that individuals with excessive alcohol consumption had a 78% increased risk of developing diabetes in comparison to those with non-excessive alcohol consumption (HR = 1.78, 95% CI 1.08-2.93). Individuals with excessive alcohol consumption were found to have a 73% higher risk of developing diabetes compared to those with non-excessive alcohol consumption, even after controlling for propensity...