Robustness of radiomics among photon-counting detector CT and dual-energy CT systems: a texture phantom study

作者：Lan Zhu, Haipeng Dong, Jing Sun, Lingyun Wang, Yue Xing, Y. Hu, Junjie Lu, Jiarui Yang, Jingshen Chu, Chao Yan, Fei Yuan, Jingyu Zhong · 发表于：European Radiology · 年份：2024 · DOI：10.1007/s00330-024-10976-1 · 被引用次数：16 · 研究领域：Advanced X-ray and CT Imaging、Radiomics and Machine Learning in Medical Imaging、Medical Imaging Techniques and Applications

OBJECTIVES: To evaluate the robustness of radiomics features among photon-counting detector CT (PCD-CT) and dual-energy CT (DECT) systems. METHODS: A texture phantom consisting of twenty-eight materials was scanned with one PCD-CT and four DECT systems (dual-source, rapid kV-switching, dual-layer, and sequential scanning) at three dose levels twice. Thirty sets of virtual monochromatic images at 70 keV were reconstructed. Regions of interest were delineated for each material with a rigid registration. Ninety-three radiomics were extracted per PyRadiomics. The test-retest repeatability between repeated scans was assessed by Bland-Altman analysis. The intra-system reproducibility between dose levels, and inter-system reproducibility within the same dose level, were evaluated by intraclass correlation coefficient (ICC) and concordance correlation coefficient (CCC). Inter-system variability among five scanners was assessed by coefficient of variation (CV) and quartile coefficient of dispersion (QCD). RESULTS: The test-retest repeatability analysis presented that 97.1% of features were repeatable between scan-rescans. The mean ± standard deviation ICC and CCC were 0.945 ± 0.079 and 0.945 ± 0.079 for intra-system reproducibility, respectively, and 86.0% and 85.7% of features were with ICC > 0.90 and CCC > 0.90, respectively, between different dose levels. The mean ± standard deviation ICC and CCC were 0.157 ± 0.174 and 0.157 ± 0.174 for inter-system reproducibility, respectively, a...