Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis

作者：Ning Li, Леи Жао, Xinyu Geng, Jingyang Liu, Xu Zhang, Ying Hu, Jihan Qi, Hongliang Chen, Jiawei Qiu, Xiaoyu Zhang, Shizhu Jin · 发表于：Theranostics · 年份：2024 · DOI：10.7150/thno.96038 · 被引用次数：90 · 研究领域：Extracellular vesicles in disease、MicroRNA in disease regulation、Cancer-related molecular mechanisms research

This study revealed a vital role for Hy-Exos in suppressing inflammatory progression in UC and suggested that miR-214-3p is a potential critical target for Hy-Exos in alleviating UC.