Enhanced Recovery After Surgery versus Conventional Care in Cholecystectomy: A Systematic Review and Meta-Analysis

作者：Jiao Qin, Jiao Qin, Ling-yan Gou, Ling-yan Gou, Wei Zhang, Xiao Pu, Ping Zhang, Ping Zhang · 发表于：Journal of Laparoendoscopic & Advanced Surgical Techniques · 年份：2024 · DOI：10.1089/lap.2024.0119 · 被引用次数：8 · 研究领域：Enhanced Recovery After Surgery、Cardiac, Anesthesia and Surgical Outcomes、Anesthesia and Pain Management

Objectives: The primary objective of this study was to evaluate the safety and efficacy of the enhanced recovery after surgery (ERAS) protocol in cholecystectomy, comparing it with standard care. Methods: A comprehensive literature search was conducted in December 2023, using globally recognized databases such as PubMed, Embase, and the Cochrane Library. Various parameters were compared using Review Manager software. This study was duly registered with PROSPERO (CRD420223). Results: The meta-analysis included nine studies, encompassing a total of 1920 patients. The findings revealed that the ERAS group, in comparison to traditional care, experienced shorter hospitalization periods (weighted mean difference [WMD]: −1.23, 95% confidence interval [CI]: −1.98 to −0.47; P = .001), lower visual analog scale at 24 hours (WMD: −1.10, 95% CI: −1.30 to −0.90; P < .00001), faster time to first flatus (WMD: −4.48, 95% CI: −4.50 to −4.46; P < .00001), and reduced operative times (WMD: −9.94, 95% CI: −17.88 to −0.96; P = .03). In addition, there was a notable decrease in instances of postoperative nausea and vomiting (odds ratio [OR]: 0.46, 95% CI: 0.28 to 0.74; P = .002). No significant differences were observed in readmission rates, blood loss, postoperative complications, or bile leakage between the two care methods. Conclusions: This study substantiates that the ERAS protocol is an advantageous perioperative care strategy for patients undergoing cholecystectomy. It significantly ...