Global burden of bladder cancer attributable to smoking in 204 countries and territories, 1990–2019

作者：Jixiang Yuan, Li‐Chen Chen, Jielong Zhou, Xinyue Zang, Tongtong Zhang, Xiran Ju, Mingyue Tan, Dongliang Xu · 发表于：Heliyon · 年份：2024 · DOI：10.1016/j.heliyon.2024.e34114 · 被引用次数：15 · 研究领域：Bladder and Urothelial Cancer Treatments、Esophageal Cancer Research and Treatment、Urinary and Genital Oncology Studies

Bladder cancer (BCa) poses a significant medical burden worldwide. However, the epidemiological pattern of the global smoking-induced BCa burden is unclear. Our analysis of the 2019 Global Burden of Disease (GBD) database showed a significant increase in the number of BCa cases worldwide from 1990 to 2019, with a clear upward trend in both age-standardized prevalence and incidence. In contrast, age-standardized rates of mortality (ASMR) and disability-adjusted life-years (ASDR) showed a downward trend, despite an increase in the absolute number of death and disability-adjusted life years. The burden of BCa caused by smoking is greater in males, middle-aged and older adults, and people in countries with high-middle socio-demographic indices (SDI). The study highlights the continuing global health challenge posed by smoking-related BCa. Targeted health policies and interventions are critical, especially in areas with high smoking rates and low socioeconomic status.