Effect of cuff inflation with lidocaine, saline, and air on tracheal tube cuff pressure during laparoscopic resection of colorectal neoplasms: a randomized clinical trial

作者：Xuan Wang, Jie Zhang, Guangli Zhu, Shenquan Cai, Qingtong Zhang, Manlin Duan, Shanwu Feng · 发表于：BMC Anesthesiology · 年份：2024 · DOI：10.1186/s12871-024-02606-6 · 被引用次数：4 · 研究领域：Abdominal Surgery and Complications、Airway Management and Intubation Techniques、Enhanced Recovery After Surgery

Abstract Background Tracheal tube cuff pressure will increase after pneumoperitoneum when the cuff is inflated with air, high pressure can cause tracheal mucosal damage. This prospective trial aimed to assess if inflating with normal saline or lidocaine can prevent increase of tracheal tube cuff pressure and tracheal mucosal damage in laparoscopic surgeries with general anesthesia. Whether changes of tracheal tube cuff transverse diameter (CD) can predict changes of tracheal tube cuff pressure. Methods Ninety patients scheduled for laparoscopic resection of colorectal neoplasms under general anesthesia were randomly assigned to groups air (A), saline (S) or lidocaine (L). Endotracheal tube cuff was inflated with room-temperature air in group A ( n = 30), normal saline in group S ( n = 30), 2% lidocaine hydrochloride injection in group L ( n = 30). After intubation, tracheal tube cuff pressure was monitored by a calibrated pressure transducers, cuff pressure was adjusted to 25 cmH 2 O (T 0.5 ). Tracheal tube cuff pressure at 15 min after pneumoperitoneum (T 1 ) and 15 min after exsufflation (T 2 ) were accessed. CD were measured by ultrasound at T 0.5 and T 1 , the ability of ΔCD (T 1-0.5 ) to predict cuff pressure was accessed. Tracheal mucous injury at the end of surgery were also recorded. Results Tracheal tube cuff pressure had no significant difference among the three groups at T 1 and T 2 . ΔCD had prediction value (AUC: 0.92 [95% CI: 0.81–1.02]; sensitivity: 0.99; speci...