The Differences on the Fatty Infiltration of Paraspinal Muscles between Single‐ and Multiple‐level Intervertebral Disc Degeneration in Patients with Lumbar Disc Herniation

作者：Minjie Shen, Zhijia Shen, Guanyu Yang, Xin Tian, Hongcheng Zhao, Wenhao Wang, Huilin Yang · 发表于：Orthopaedic Surgery · 年份：2024 · 被引用次数：17 · 研究领域：Spine and Intervertebral Disc Pathology、Spinal Hematomas and Complications、Musculoskeletal pain and rehabilitation

OBJECTIVE: Multiple-level Intervertebral disc degeneration (IDD) in patients with lumbar disc herniation (LDH) is related to postoperative re-herniation and low back pain. Although many investigators believed that there is an interdependence between paraspinal muscles degeneration and IDD, few studies focused on the fatty infiltration of paraspinal muscles on single- and multiple-level IDD in patients with LDH. This study aims to investigate the difference on the fatty infiltration of paraspinal muscles between single- and multiple-levels IDD in patients with LDH. and to explore in patients with LDH whether fatty infiltration is a potential risk factor for multiple-level IDD. METHODS: This study was conducted as a retrospective observational analysis of 82 patients with LDH from January 1, 2020 to December 30, 2020 in our hospital were enrolled. Twenty-seven cases had single-level IDD (Group A), and 55 cases had multiple-level IDD (Group B). We measured the mean computed tomography (CT) density value of the paraspinal muscles, including multifidus (MF), erector spinae (ES) and psoas muscle (PM) at each disc from L1 to S1. Subgroups were set to further analyze the odds ratio (OR) of fatty infiltration of paraspinal muscles in different sex and BMI groups. We measured sagittal angles and analyzed the relationships between these angles and IDD. Finally, we use logistic regression, adjusted for other confounding factors, to investigate whether fatty infiltration is an independent...