A copper-catalyzed annulation reaction of diazo esters with propargyl amines for the synthesis of 2,5-dihydropyrroles

作者：Haodong Xie, Zhao Wei, Heping Wei, Yang Yu, Lili Zhao, Jonathan B. Baell, Fei Huang · 发表于：Organic Chemistry Frontiers · 年份：2024 · DOI：10.1039/d4qo00751d · 被引用次数：3 · 研究领域：Cyclopropane Reaction Mechanisms、Catalytic Alkyne Reactions、Catalytic C–H Functionalization Methods

An efficient protocol for the synthesis of 2,5-dihydropyrroles using diazo esters and propargyl amines has been reported, featuring mild reaction conditions, straightforward operation, the absence of metal ligands, and high atom economy.