New alternatives to holder pasteurization in processing donor milk in human milk banks

作者：Guido E. Moro, M Girard, Chiara Peila, Nadia Garcia, Diana Escuder‐Vieco, Kristin Keller, Tanya Cassidy, Enrico Bertino, Clair‐Yves Boquien, Rachel Buffin, Javier Calvo, Antoni Gayà, Corinna Gebauer, Delphine Lamireau, David Lembo, Jean‐Charles Picaud, Aleksandra Wesołowska, Sertaç Arslanoğlu, Laura Cavallarin, Marzia Giribaldi · 发表于：Frontiers in Nutrition · 年份：2024 · DOI：10.3389/fnut.2024.1409381 · 被引用次数：14 · 研究领域：Infant Nutrition and Health、Viral gastroenteritis research and epidemiology、Microbial Inactivation Methods

Infectious and toxicological risks are the main potential hazards that operators of Human Milk Banks (HMBs) encounter and must eliminate. HMBs are trying to implement procedures that allow to manage and sanitize human milk without altering significantly its nutritional and biologically protective components, obtaining a product characterized by a valid balance between safety and biological quality. The history of human milk processing is linked to the origins of HMBs themselves. And although other forms of sterilization were used originally, pasteurization soon became the recognized most effective means for sanitizing milk: all the milk that arrives at the HMB must be pasteurized. Holder pasteurization (HoP) is the most used methodology, and it is performed using low temperature and long time (+62.5°C for 30 min). With HoP some bioactive milk components are lost to varying degrees, but many other precious bioactive compounds are completely or partially preserved. To improve the quality of human milk processed by HMBs, maintaining in the meantime the same microbiological safety offered by HoP, new technologies are under evaluation. At present, High-Temperature Short-Time pasteurization (HTST) and High-Pressure Processing are the most studied methodologies. HTST is already utilized in some HMBs for daily practical activity and for research purposes. They seem to be superior to HoP for a better preservation of some nutritional and biologically protective components. Freeze-dryin...