Association between plant-based dietary index and gallstone disease: A cross sectional study from NHANES

作者：Luyang Li, Chengli Liu, Tian Xia, Hao-Ming Li, Jun Yang, Pu Meng, Shuhan Zhang, Yingbo Ma, Tao Zhang · 发表于：PLoS ONE · 年份：2024 · DOI：10.1371/journal.pone.0305822 · 被引用次数：6 · 研究领域：Gallbladder and Bile Duct Disorders、Appendicitis Diagnosis and Management、Congenital Anomalies and Fetal Surgery

BACKGROUND: The relationship between plant-based diets and gallstone disease has been debated. This study aimed to shed light on the association between plant-based dietary index and the risk of developing gallstone disease. METHODS: Eligible participants were selected from National Health and Nutrition Examination Survey (NHANES) 2017-2020. Three plant-based diet indexes (PDI, healthy PDI, unhealthy PDI) were calculated using data from two NHANES 24-h dietary recall interviews. Restricted Cubic Spline and multivariate logistic regression were used to analyze the associations. Subgroup analysis was adopted to make the results more robust. RESULTS: A total of 5673 eligible participants were analyzed. After adjusting for various confounding variables, uPDI was positively associated with gallstone disease (OR = 1.53, 95%CI: 1.02-2.29). No association was found between PDI/hPDI and gallstone disease (p > 0.05). The results of subgroup analysis did not show any positive association between uPDI and gallstones in specific groups. CONCLUSION: Our study shows that the elevated uPDI are linked to a higher risk of gallstone disease.