The Guidelines for use and promotion of low sodium salt in China

作者：Yifang Yuan, Chao Gao, Xuejun Yin, Xianghui Zhang, Yufei Ji, Xizi Zheng, Qi Zhou, Yangfeng Wu · 发表于：Journal of Evidence-Based Medicine · 年份：2024 · DOI：10.1111/jebm.12621 · 被引用次数：10 · 研究领域：Sodium Intake and Health、Magnesium in Health and Disease、Potassium and Related Disorders

AIM: Both excessive intake of sodium and inadequate intake of potassium are associated with blood pressure elevation and subsequent increase in the risk of cardiovascular disease, which accounts for the largest number of deaths in China and worldwide. Low sodium salt, a mixture of mainly sodium chloride and potassium chloride, has shown its great potential as a promising population strategy for sodium intake reduction through multiple large-scale, multicenter, randomized controlled trials among populations including patients with cardiovascular disease, individuals with and without hypertension, older and younger adults, and men and women in China and other countries. This Guidelines aims to provide expert recommendations for promotion and use of low sodium salt in China, based on the current available scientific evidence regarding the effectiveness, safety, cost-effectiveness, and acceptability of low sodium salts in various population groups and different application scenarios. The suggestions to key stakeholders are also made. METHODS: A working group, an expert review committee and an advisory committee were established to be responsible for formulating the guidelines' scope and key questions to be addressed, for searching, synthesizing, and evaluating research evidence, proposing and reviewing the recommendations. The consensus on the final recommendations was reached using the GRADE grid method. RESULTS: The working group summarized current available evidence of salt su...