Deciphering m6A methylation in monocyte-mediated cardiac fibrosis and monocyte-hitchhiked erythrocyte microvesicle biohybrid therapy

作者：Jiawen Li, Wei Li, Kaifeng Hu, Yunxiang He, Guidong Gong, Qisong Liu, Yue Zhang, Kaiyu Zhou, Junling Guo, Yimin Hua, Jun Tang, Yifei Li · 发表于：Theranostics · 年份：2024 · DOI：10.7150/thno.95664 · 被引用次数：18 · 研究领域：Cardiac Structural Anomalies and Repair、RNA modifications and cancer、Peptidase Inhibition and Analysis

A modifications of monocytes with STM2457, delivered via erythrocyte microvesicles, reduces inflammation and fibrosis, offering a promising therapeutic strategy for cardiac remodeling associated with device implantation.