Diabetic Myocardial Disorder. A Clinical Consensus Statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases

作者：Petar Seferović, Walter J. Paulus, Giuseppe Rosano, Marija Polovina, Mark C. Petrie, Pardeep S. Jhund, Carsten Tschöpe, Naveed Sattar, Massimo Piepoli, Z. Papp, Eberhard Standl, Mamas Mamas, Paul Valensi, Aleš Linhart, Nebojša Lalić, Antonio Ceriello, Wolfram Döhner, Arsen Ristić, Ivan Milinković, Jelena Seferović, Francesco Cosentino, Marco Metra, Andrew J.S. Coats · 发表于：European Journal of Heart Failure · 年份：2024 · 被引用次数：87 · 研究领域：Cardiovascular Function and Risk Factors、Diabetes Treatment and Management、Metabolism, Diabetes, and Cancer

The association between type 2 diabetes mellitus (T2DM) and heart failure (HF) has been firmly established; however, the entity of diabetic myocardial disorder (previously called diabetic cardiomyopathy) remains a matter of debate. Diabetic myocardial disorder was originally described as the occurrence of myocardial structural/functional abnormalities associated with T2DM in the absence of coronary heart disease, hypertension and/or obesity. However, supporting evidence has been derived from experimental and small clinical studies. Only a minority of T2DM patients are recognized as having this condition in the absence of contributing factors, thereby limiting its clinical utility. Therefore, this concept is increasingly being viewed along the evolving HF trajectory, where patients with T2DM and asymptomatic structural/functional cardiac abnormalities could be considered as having pre-HF. The importance of recognizing this stage has gained interest due to the potential for current treatments to halt or delay the progression to overt HF in some patients. This document is an expert consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases. It summarizes contemporary understanding of the association between T2DM and HF and discuses current knowledge and uncertainties about diabetic myocardial disorder that deserve future research. It also proposes a new definition, whereby diabetic myocardial disorder is defined...