Research Progress on Ti3C2Tx-Based Composite Materials in Antibacterial Field

作者：Huangqin Chen, Yilun Wang, Xuguang Chen, Zihan Wang, Yue Wu, Qiongqiao Dai, Wenjing Zhao, Wei Tian, Qingyuan Yang, Bin Huang, Yuesheng Li · 发表于：Molecules · 年份：2024 · DOI：10.3390/molecules29122902 · 被引用次数：17 · 研究领域：MXene and MAX Phase Materials、Advanced Photocatalysis Techniques、2D Materials and Applications

The integration of two-dimensional Ti3C2Tx nanosheets and other materials offers broader application options in the antibacterial field. Ti3C2Tx-based composites demonstrate synergistic physical, chemical, and photodynamic antibacterial activity. In this review, we aim to explore the potential of Ti3C2Tx-based composites in the fabrication of an antibiotic-free antibacterial agent with a focus on their systematic classification, manufacturing technology, and application potential. We investigate various components of Ti3C2Tx-based composites, such as metals, metal oxides, metal sulfides, organic frameworks, photosensitizers, etc. We also summarize the fabrication techniques used for preparing Ti3C2Tx-based composites, including solution mixing, chemical synthesis, layer-by-layer self-assembly, electrostatic assembly, and three-dimensional (3D) printing. The most recent developments in antibacterial application are also thoroughly discussed, with special attention to the medical, water treatment, food preservation, flexible textile, and industrial sectors. Ultimately, the future directions and opportunities are delineated, underscoring the focus of further research, such as elucidating microscopic mechanisms, achieving a balance between biocompatibility and antibacterial efficiency, and investigating effective, eco-friendly synthesis techniques combined with intelligent technology. A survey of the literature provides a comprehensive overview of the state-of-the-art development...