Comparison of an Affibody-based Molecular Probe and 18 F-FDG for Detecting HER2-Positive Breast Cancer at PET/CT

作者：Xiaoyi Guo, Nina Zhou, Jiayue Liu, Jin Ding, Teli Liu, Guohong Song, Hua Zhu, Zhi Yang · 发表于：Radiology · 年份：2024 · DOI：10.1148/radiol.232209 · 被引用次数：25 · 研究领域：Monoclonal and Polyclonal Antibodies Research、Advanced Biosensing Techniques and Applications、Radiopharmaceutical Chemistry and Applications

In participants with human epidermal growth factor receptor 2–positive breast cancer, the affibody-based tracer Al 18 F-NOTA-HER2-BCH enabled detection of more primary lesions and lymph node, bone, and liver metastases than fluorine 18 fluorodeoxyglucose on PET/CT images.