Gnaiger E and the MitoEAGLE task group. Mitochondrial physiology

作者：Gnaiger, Erich, Aasander Frostner, Eleonor, Abdul Karim, Norwahidah, E. Abdelrahman, Nada A. Abumrad, Darı́o Acuña-Castroviejo, Reginald Adiele, Bumsoo Ahn, Mayke Bezerra Alencar, Sameh S. Ali, Ángeles Almeida, Lesley A. Alton, Marco Túlio Santana Alves, Francesca Amati, Nívea Dias Amoêdo, Ricardo Amorim, Ethan Anderson, Ioanna Andreadou, Diana Antunes, Marc Arago, Cenk Aral, Odeta Arandarčikaitė, Christian Arias‐Reyes, Anne‐Sophie Armand, Thierry Arnould, Vlad Florian Avram, Christopher L. Axelrod, Aïda Bairam, Damian M. Bailey, Sudip Bajpeyi, Martina Bajzíková, Barbara M. Bakker, Jonathan Barlow, Tora Bardal, A Banni, Bastos Sant'Anna Silva, Ana Carolina, Philip M. Batterson, Maurizio Battino, Jason N. Bazil, Daniel Beard, Jorge Beleza, Piotr Bednarczyk, Fiona Bello, Dorit Ben‐Shachar, Bento Guida, Jose Freitas, Andreas Bergdahl, Rolf K. Berge, Lisa Bergmeister, Paolo Bernardi, Michael V. Berridge, Stefano Bettinazzi, David J. Bishop, Pierre Blier, Dan Filip Blindheim, Boardman, Neoma, Hans Erik Boetker, Sabine Borchard, Mihály Boros, Elisabet Børsheim, Consuelo Borrás, Vilma Borutaite, Javier Botella, Frédéric Bouillaud, Jamal Bouitbir, Robert Boushel, Josh Bovard, Roberto Bravo, Sophie Breton, David C. Brown, Guy C. Brown, Robert N. Brown, Joseph T. Brozinick, Garry R. Buettner, Johannes Burtscher, Matilde Bustos, Elisa Calabria, José A. L. Calbet, Enrico Calzia, Daniel E. Cannon, Cano Sanchez, Maria, Canto Alvarez, Carles, Daniele A. Cardinale, Luiza H.D. Cardoso, Eugénia Carvalho, Casado Pinna, Marta, Samantha Cassar, Maria Helane Costa Gurgel Castelo, Roger F. Castilho, João Paulo Cavalcanti‐de‐Albuquerque, Cecatto, Cristiane, Celen, Murat, Zuzana Červinková, Béatrice Chabi, Lisa Chakrabarti, Sasanka Chakrabarti, Bhagirath Chaurasia, Quan Chen, Adam J. Chicco, Christos Chinopoulos, Subir Roy Chowdhury, Beáta Čižmárová, Emilio Clementi, Paul M. Coen, Bruce S. Cohen, Coker, Robert, Collin-Chenot, Anne, Melinda T. Coughlan, Petro Coxito, Luís Crisóstomo, Marcell Crispim, Hannah Crossland, Norma Dahdah, Louise T. Dalgaard, Maija Dambrova, Tereza Daňhelovská, Charles Darveau, Paula M. Darwin, Anibh M. Das, Ranjan Dash, Eliška Davidová, Michael Davis, Sudarshan Dayanidhi, Andreza Fabro de, Paul de Goede, Clara De Palma, de Pinto, Vito, Flemming Dela, A. Dembińska-Kieć, Damien Detraux, Yvan Devaux, Marco Di Marcello, Di Paola, Floriana Jessica, Cândida Dias, Tânia R. Dias, Marc Diederich, Giovanna Distéfano, Siamak Djafarzadeh, Niklas Doermann, Carolina Doerrier, Lan‐Feng Dong, Chris Donnelly, Z Drahota, Filipe V. Duarte, Hervé Dubouchaud, Michael R. Duchen, Jean‐François Dumas, William H. Durham, Dorota Dymkowska, Sissel E. Dyrstad, Alex Dyson, Edward Dzialowski, Simon Eaton, Johannes K. Ehinger, Eskil Elmér, René Endlicher, Ayşe Başak Engin, Germaine Escames, Andrea Evinová, Zuzana Ezrova, Marni J. Falk, David A. Fell, Péter Ferdinándy, Miroslav Ferko, Marisol Fernández‐Ortiz, Erika, Fernandez-Vizarra, Julio Cesar Batista Ferreira, Rita Ferreira, Alessandra Ferri, Wt Festuccia, Joshua P. Fessel, Aleksandra Filipovska, Zdeněk Fišar, Christine Fischer, Michael Fischer, Gordon Fisher, Joshua B. Fisher, Flavia Fontanesi, Tamara Y. Forbes‐Hernández, Ellen Ford, Mara Fornaro, Fuertes Agudo, Marina, Montana Fulton, Antônio Galina, Alexander Galkin, Leon Gallee, Gina L. J. Galli, Gama Perez, Pau, Zhenji Gan, Rebecca Ganetzky, Yun Gao, Geovana S. Garcia, Gerardo García‐Rivas, Pablo M. García-Rovés, Luiz F. Garcia‐Souza, Keith Garlid, Glòria Garrabou, Antje Garten, Amalia Gastaldelli, Jiaur R. Gayen, Amanda J. Genders, Maria Luisa Genova, Francesca Giampieri, Jan F. C. Glatz, Matteo Giovarelli, Goikoetxea Usandizaga, Naroa, Goncalo Teixeira da Silva, Rui, Debora Farina Goncalves, Jenny Gonzalez-Armenta, Gonzalez-Francesqua, A, Marta González‐Freire, Hugo Gonzalo‐Benito, Bret H. Goodpaster, Thomas A. Gorr, Campbell W. Gourlay, Bente Grams, Cesare Granata, Sander Grefte, Luís F. Grilo, Meritxell Espino Guarch, Naïg Guéguen, Sentiljana Gumeni, Clarissa Branco Haas, Jan Haavik, Yafit Hachmo, Judith Haendeler, Markus Haider, Anesa Hajrulahovic, Andréa Hamann, Jin Han, Woo Hyun Han, Chad R. Hancock, Steven Hand, Jiří Handl, Hana Hansíková, Justin P. Hardee, Ian S. Hargreaves, Mary Ellen Harper, David K. Harrison, Hazirah Hassan, Hatakova, Zuzana, Derek J. Hausenloy, Simon Heales, Christina Heiestad, Kim T. Hellgren, Henrique Alexandrino, Russell T. Hepple, Pablo Hernansanz‐Agustín, Sudinna Hewakapuge, Anthony J. Hickey, Dieu Hien Ho, Kyle L. Hoehn, Frederik Hoel, Olivia J. Holland, Graham P. Holloway, Lorenz J. Holzner, Charles L. Hoppel, Hans Hoppeler, Florian Hoppel, J Houštěk, María Huete‐Ortega, Petra Hyroššová, Javier Iglesias‐González, Cesare Indiveri, Brian A. Irving, Raffaella Isola, Shilpa Iyer, Christophe Jackson, Pooja Jadiya, Prado Fabian Jana, Karin Jandeleit‐Dahm, David W. Jang, Young Jang, Joanna Janowska, Kirsten M. Jansen, Pidder Jansen‐Dürr, Baiba Jansone, Wiesława Jarmuszkiewicz, Anna Jaśkiewicz, Richard T. Jaspers, Jan Jedlička, Estaquier Jerome, Nichlas Jespersen, Rajan Jha, Vincent Joseph, László Juhász, Michael J. Jurczak, Diana Jurk, Tuuli Käämbre, Jan Jacek Kaczor, Heikki Kainulainen, Rafał Paweł Kampa, Sunil Kandel, Daniel A. Kane, Werner Kapferer, Senta M. Kapnick, Lisa Kappler, Alexander Karabatsiakis, Iuliia Karavaeva, Agnieszka Karkucińska‐Więckowska, Sarbjot Kaur, Jaap Keijer, Markus Keller, Gloria Keppner, Andy V. Khamoui, Dita Kidere, Todd J. Kilbaugh, Hyoung Kyu Kim, Julian Ks Kim, Sammy Kimoloi, Aleksandr Klepinin, Lyudmila Klepinina, Martin Klingenspor, Helmut Klocker, Tímea Komlódi, Iris Kolasa, Werner J.H. Koopman, Nataša Kopitar‐Jerala, Alicia J. Kowaltowski, А. P. Kozlov, Adéla Krajčová, Krako Jakovljevic, Nina, Bruce S. Kristal, Jamer Krycer, Jujiao Kuang, Otto Kučera, Janis Kuka, Hyo Bum Kwak, Kurt E. Kwast, Kwon, Oh Sung, Martin Laasmaa, Magdalena Łabieniec-Watała, Nicola Lai, Nebojša Lalić, John M. Land, Nick Lane, Verena Laner, Ian R. Lanza, Sofien Laouafa, Steen Larsen, Terje H. Larsen, Gareth G. Lavery, Antigone Lazou, Ledo, Ana Margarida, Hong Kyu Lee, Christiaan Leeuwenburgh, Maarit Lehti, Hélène Lemieux, Giorgio Lenaz, Jørgen Lerfall, Pingan Li, Li Puma, Lance, Liping Liang, Edgars Liepinsh, Chien‐Te Lin, Jiankang Liu, Luis Martı́nez, Eliana Lucchinetti, Tao Ma, Maria do Socorro Alencar Nunes Macedo, Ivo Machado, Sarah Maciej, Lee Ann MacMillan-Crow, José Magalhães, Andrea Magrì, Pavlína Majtnerová, E. Kh. Makarova, Marina Makrecka‐Kuka, Afshan N. Malik, François Marcouiller, Amandine Maréchal, M. N. Markova, Ivanka Marković, Daniel J. Martin, Ana D. Martins, João Paulo Martins, Tumisang Edward Maseko, Felicia Maull, Jean Pierre Mazat, Helen McKenna, Matthew McKenzie, Mcmillan, Duncan Gg, Gavin P. McStay, Michael A. Menze, Amy E. Mendham, John A. Mercer, Tamara Merz, Angela Messina, András Mészáros, Axel Methner, S. Michalak, Mila Guasch, Maria, Luciéle Guerra Minuzzi, Misirkic Marjanovic, Maja, Douglas Moellering, Nicoleta Moisoi, Anthony Ja Molina, David Montaigne, Anthony L. Moore, Christy Moore, Kerrie L. Moreau, Bruno Moreira, Rafael Moreno-Sanchez, Tomáš Mráček, Anna Maria Muccini, Jordi Muntané, Danina Muntean, Andrew Murray, Eva Musiol, Miranda Nabben, K. Sreekumaran Nair, Jan O. Nehlin, Michal Nemec, Salvatore Nesci, P. Darrell Neufer, Jiřı́ Neužil, Rémi Nevière, Sean A. Newsom, Jennifer Norman, Katerina Nozickova, Sara Nunes, Jean‐Marc Nuoffer, Kristin M. O’Brien, Katie O'Brien, Donal J. O’Gorman, Yusuf Olğar, Ben Oliveira, Jorge Oliveira, Marcus Oliveira, Marcos T. Oliveira, Oliveira, Pedro, Paulo Oliveira, Rolf Erik Olsen, Zulfiya Orynbayeva, Heinz D. Osiewacz, Hector G. Paez, Youngmi Pak, Maria Pallotta, Carlos M. Palmeira, Nirmala Parajuli, João F. Passos, Manuela Passrugger, Hemal Patel, Nadia Pavlova, Kasja Pavlović, Petr Pecina, T Pedersen, José C. Perales, Pereira da Silva Grilo da Silva, Filomena, Rita Pereira, Perez Valencia, Juan, Perks, Kara, Dominik Pesta, Patrice X. Petit, Pettersen Nitschke, Ina Katrine, Nicolas Pichaud, Irene Pichler, Piel, Sarah, Terri Pietka, Sónia L. C. Pinho, Maria Pino, Sergej Pirkmajer, Nicolas Place, Mario Plangger, Craig Porter, Richard K. Porter, Preguica, Ines, Vincent Procaccio, Edward V. Prochownik, Alexandre Prola, Thomas Pulinilkunnil, Michael A. Puskarich, Marju Puurand, Filip Radenkovic, Rabia Ramzan, Suresh I. S. Rattan, Simone Reano, Patricia Reboredo‐Rodríguez, B. Rees, Kathrin Renner-Sattler, Eduardo Rial, Matthew Robinson, Michael Roden, Ana S. M. C. Rodrigues, Enrique Rodrı́guez, Sara Rodríguez‐Enríquez, Gro Vatne Roesland, Anabela P. Rolo, Eduardo R. Ropelle, Baback Roshanravan, Rodrigue Rossignol, Harry B. Rossiter, Tomáš Roušar, Ivica Rubelj, Joanna Rybacka-Mossakowska, Ann Saada, Zahra Safaei, Saharnaz Sarlak, Karine Salin, Desy Salvadego, Carmen Sandi, Nicholas J. Saner, Diana Santos, Alberto Sanz, Vilma A. Sardão, Leonid A. Sazanov, Paula J. Scaife, Roberto Scatena, Melanie Schartner, Morten Scheibye‐Knudsen, Jan M. Schilling, Uwe Schlattner, Sabine Schmitt, Schneider Gasser, Edith Mariane, Peter Schoenfeld, Pauke C. Schots, Rainer Schulz, Christoph Schwarzer, Graham Scott, Colin Selman, Sendon, Pamella Marie, Irina G. Shabalina, Pushpa Sharma, Vipin Sharma, Igor V. Shevchuk, Reza Shirazi, Jonathan Shiroma, Karolina Siewiera, Ariel Mariano Silber, Ana Carolina Bastos Sant'Anna Silva, Carrie A. Sims, Dominique Singer, Brijesh Kumar Singh, Robert Skolik, Smenes, Benedikte Therese, James F. Smith, Félix Alexandre Antunes Soares, Ondřej Sobotka, Inna M. Sokolova, Solesio Torregrosa, M de la Encarnacion, Jorge Soliz, Vijay K. Sonkar, Marina Sova, Alice P. Sowton, Genevieve C. Sparagna, Lauren Sparks, Marco Spinazzi, Pavla Staňková, Jonathan Starr, Creed M. Stary, Eduard Stefan, Gundega Stelfa, Nigel K. Stepto, Jelena Stevanović, Johnny Stiban, Antoine Stier, Roland Stocker, Julie Storder, Zuzana Sumbalová, Wartiovaara Anu Suomalainen, Prashanth Suravajhala, Baiba Švalbe, Russel Swerdlow, Daria Świniuch, Ildikò Szabó, Adam Szewczyk, Marten Szibor, Masashi Tanaka, Bernard Tandler, Mark A. Tarnopolsky, Daniel Tausan, Nektarios Tavernarakis, Kersti Tepp, J Teodoro, Himani Thakkar, Maheshwo Thapa, John P. Thyfault, Dhanendra Tomar, Riccardo Ton, May‐Kristin Torp, Omar Torres‐Quesada, Atif Towheed, Jason R. Treberg, László Tretter, Trewin, Adam, Trifunovic, Aleksandra, Catherine Trivigno, Karl Johan Tronstad, Ioannis P. Trougakos, Laura Truu, Erkan Tuncay, Belma Turan, Daniel J. Tyrrell, Tomáš Urban, Sofia Urner, Joseph M. Valentine, Nicole Bergen, Miranda van der Ende, Frederick Varricchio, Peter Vaupel, Joanna Vella, Marko Vendelin, Verdaguer, Ib, Anı́bal E. Vercesi, Andrea Vernerová, Víctor M. Víctor, Vieira Ligo Teixeira, Camila, Josif Vidimce, Christian Viel, Adalberto Vieyra, Kārlis Vilks, Josep A. Villena, Vinnyfred Vincent, A. S. Vinogradov, Carlo Viscomi, Rui Vitorino, Vlachaki Walker, Julia, Sebastian Vogt, Chiara Volani, Kristine Volska, Dominique Votion, Ksenija Vujacic-Mirski, Brett A. Wagner, Marie Louise Ward, Verena Warnsmann, David Wasserman, Cezary Watała, Yau‐Huei Wei, Klaus M. Weinberger, Sarah White, Jamie Whitfield, Anika Wickert, Mariusz R. Wiȩckowski, Rudolf J. Wiesner, Caroline Williams, Hugh Winwood-Smith, Stephanie E. Wohlgemuth, Martin Wohlwend, Jonci N. Wolff, Chantal Wrutniak‐Cabello, Rob Wuest, Takashi Yokota, Krzysztof Zabłocki, Alessandra Zanon, Nadège Zanou, Kathrin Zaugg, Michael Zaugg, Lucie Zdražilová, Yong Zhang, Yi Zhu Zhang, Alena Zı́ková, Hans Zischka, Antonio Zorzano, T. Zujovic, Jitka Žurmanová, Liga Zvejniece, Sandrine Lagarrigue, Daniel Munro, Susana Pereira, João Laranjinha, Ángeles Almeida, Marc Diederich, Matthias Hecker, Amela Jusić, Alessandro Prigione, Natascha Sommer, Volkmar Weissig, Guida, Bento,, John G, Jones, Jg · 发表于：ORBi (University of Liège) · 年份：2020 · DOI：10.26124/bec:2020-0001.v1 · 被引用次数：26 · 研究领域：Mitochondrial Function and Pathology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ul...