Changes in the prevalence of mental health problems during the first year of the pandemic: a systematic review and dose-response meta-analysis

作者：Georgia Salanti, Natalie Peter, Thomy Tonia, Alexander Holloway, Leila Darwish, Ronald C. Kessler, Ian R. White, Simone N. Vigod, Matthias Egger, Andreas D. Haas, Seena Fazel, Helen Herrman, Christian Kieling, Vikram Patel, Tianjing Li, Pim Cuijpers, Andrea Cipriani, Toshi A. Furukawa, Stefan Leucht · 发表于：BMJ Mental Health · 年份：2024 · DOI：10.1136/bmjment-2024-301018 · 被引用次数：13 · 研究领域：COVID-19 and Mental Health、COVID-19 and healthcare impacts、Long-Term Effects of COVID-19

AIM: To describe the pattern of the prevalence of mental health problems during the first year of the COVID-19 pandemic and examine the impact of containment measures on these trends. METHODS: We identified articles published until 30 August 2021 that reported the prevalence of mental health problems in the general population at two or more time points. A crowd of 114 reviewers extracted data on prevalence, study and participant characteristics. We collected information on the number of days since the first SARS-CoV-2 infection in the study country, the stringency of containment measures and the number of cases and deaths. We synthesised changes in prevalence during the pandemic using a random-effects model. We used dose-response meta-analysis to evaluate the trajectory of the changes in mental health problems. RESULTS: We included 41 studies for 7 mental health conditions. The average odds of symptoms increased during the pandemic (mean OR ranging from 1.23 to 2.08). Heterogeneity was very large and could not be explained by differences in participants or study characteristics. Average odds of psychological distress, depression and anxiety increased during the first 2 months of the pandemic, with increased stringency of the measures, reported infections and deaths. The confidence in the evidence was low to very low. CONCLUSIONS: We observed an initial increase in the average risk of psychological distress, depression-related and anxiety-related problems during the first 2 mo...