Association of weight-adjusted waist index with all-cause mortality among non-Asian individuals: a national population-based cohort study

作者：Ting Cao, Ruijie Xie, Jiusong Wang, Meimei Xiao, Haiyang Wu, Xiaozhu Liu, Songlin Xie, Yanming Chen, Mingjiang Liu, Ya Zhang · 发表于：Nutrition Journal · 年份：2024 · DOI：10.1186/s12937-024-00947-z · 被引用次数：37 · 研究领域：Diabetes, Cardiovascular Risks, and Lipoproteins、Bariatric Surgery and Outcomes、Obesity, Physical Activity, Diet

INTRODUCTION: The Weight-Adjusted Waist Index (WWI) is a new indicator of obesity that is associated with all-cause mortality in Asian populations. Our study aimed to investigate the linear and non-linear associations between WWI and all-cause mortality in non-Asian populations in the United States, and whether WWI was superior to traditional obesity indicators as a predictor of all-cause mortality. METHODS: We conducted a cohort study using data from the 2011-2018 National Health and Nutrition Examination Survey (NHANES), involving 18,592 participants. We utilized Cox proportional hazard models to assess the association between WWI, BMI, WC, and the risk of all-cause mortality, and performed subgroup analyses and interaction tests. We also employed a receiver operating characteristics (ROC) curve study to evaluate the effectiveness of WWI, BMI, and WC in predicting all-cause mortality. RESULTS: After adjusting for confounders, WWI, BMI, and WC were positively associated with all-cause mortality. The performance of WWI, BMI, and WC in predicting all-cause mortality yielded AUCs of 0.697, 0.524, and 0.562, respectively. The data also revealed a U-shaped relationship between WWI and all-cause mortality. Race and cancer modified the relationship between WWI and all-cause mortality, with the relationship being negatively correlated in African Americans and cancer patients. CONCLUSIONS: In non-Asian populations in the United States, there is a U-shaped relationship between WWI and...