Amide-Based Porous Organic Polymers for Efficient Loading of Photosensitizers and Production of Reactive Oxygen Species for Antimicrobial Applications

作者：Kexin Zhang, Wei Wu, Ji Fan, Yi Zhong, Linping Zhang, Hong Xu, Zhiping Mao, Bolin Ji · 发表于：ACS Applied Polymer Materials · 年份：2024 · DOI：10.1021/acsapm.4c00716 · 被引用次数：7 · 研究领域：Covalent Organic Framework Applications、Advanced Photocatalysis Techniques、Metal-Organic Frameworks: Synthesis and Applications

The aggregation-caused quenching (ACQ) effect of photosensitizers (PSs) damages its photosterilization efficiency. Herein, two amide-bond connected porous organic polymers (POPs) containing a benzophenone structure (POP-1) and no benzophenone structure (POP-2) were designed and obtained. The high specific surface area (197.3 m 2 /g) and pore size (4.260 nm) of POP-1 enabled Rose Bengal (RB) to be efficiently trapped in POP-1 (RB@POP-1). Similarly, POP-2 showed a specific surface area of 28.63 m 2 /g and a pore size of 3.409 nm, which also ensured the capture of RB. Adsorption of RB by POP-1 decreased with increasing pH; and the equilibrium adsorption capacity ( q e ) of POP-1 for RB reached about 27.88 mg/g (the initial concentration of RB solution was 350.0 mg/L). The adsorption conformed to the Freundlich adsorption isotherm model and the pseudo-first-order kinetic adsorption model. The amount of reactive oxygen species (ROS) produced by RB@POP-1 and RB@POP-2 increased by 24.25% and 332.0%, respectively, compared with that produced by only POP-1 and POP-2, which mainly benefited from three aspects: (I) the separation distribution of RB molecules in the mesopores of POP-1 or POP-2 significantly decreased the ACQ effect; (II) the benzophenone structure and RB molecule of RB@POP-1 synergistically produced ROS under the light irradiation, resulting in a better antimicrobial effect of RB@POP-1 compared to the POP-1 and RB@POP-2; (III) besides the singlet oxygen ( 1 O 2 ), the hy...