B7-H3: a robust target for immunotherapy in prostate cancer

作者：Rafael Pulido, José I. López, Caroline E. Nunes‐Xavier · 发表于：Trends in cancer · 年份：2024 · DOI：10.1016/j.trecan.2024.05.003 · 被引用次数：21 · 研究领域：Immunotherapy and Immune Responses、Cancer Immunotherapy and Biomarkers、Prostate Cancer Treatment and Research

B7-H3, an immune checkpoint glycoprotein, facilitates immune evasion and the promotion of tumors and is highly expressed on the surface of prostate cancer (PCa) cells, which makes it a feasible and robust candidate for immunotherapies against advanced prostate cancer. Here, we summarize and discuss recent findings on the suitability of targeting B7-H3 in PCa treatment.