Outbreak of Highly Pathogenic Avian Influenza A(H5N1) Viruses in U.S. Dairy Cattle and Detection of Two Human Cases — United States, 2024

作者：Shikha Garg, Carrie Reed, C. Todd Davis, Timothy M. Uyeki, Casey Barton Behravesh, Krista Kniss, Alicia Budd, Matthew Biggerstaff, Jennifer Adjemian, John Barnes, Marie K. Kirby, Colin Basler, Christine M. Szablewski, Malia Richmond-Crum, Erin Burns, Brandi Limbago, Demetre Daskalakis, Kimberly L. Armstrong, David Boucher, Tom T. Shimabukuro, Michael A. Jhung, Sonja J. Olsen, Vivien G. Dugan · 发表于：MMWR Morbidity and Mortality Weekly Report · 年份：2024 · DOI：10.15585/mmwr.mm7321e1 · 被引用次数：130 · 研究领域：Influenza Virus Research Studies、Animal Disease Management and Epidemiology、Viral gastroenteritis research and epidemiology

On April 1, 2024, the Texas Department of State Health Services reported that a dairy farm worker had tested positive for highly pathogenic avian influenza A(H5N1) virus after exposure to presumably infected dairy cattle; CDC confirmed these laboratory findings.A(H5N1) viruses were found in high concentrations in unpasteurized (raw) milk from infected cows.CDC is collaborating with the U.S. Department of Agriculture, the Food and Drug Administration, the Administration for Strategic Preparedness and Response, the Health Resources and Services Administration, the National Institute of Allergy and Infectious Diseases, and state and local public health and animal health officials using a coordinated One Health approach to identify and prepare for developments that could increase the risk to human health.Activities include monitoring of exposed persons, conducting syndromic and laboratory surveillance, planning epidemiologic investigations, and evaluating medical countermeasures.As of May 22, 2024, approximately 350 farm workers with exposure to dairy cattle or infected raw cow's milk had been monitored.These monitoring efforts identified a second human A(H5) case with conjunctivitis in Michigan, which was reported on May 22, 2024.CDC considers the current risk to the U.S. public from A(H5N1) viruses to be low; however, persons with exposure to infected animals or contaminated materials, including raw cow's milk, are at higher risk for A(H5N1) virus infection and should take reco...