Encapsulation of a small-molecule drug based on substituted 2-aminothiophenes in calcium carbonate carriers for therapy of melanoma
作者:Timofey E. Karpov, Anna Rogova, Darya R. Akhmetova, Yulia A. Tishchenko, Anastasia V. Chinakova, D. V. Lipin, Nina V. Gavrilova, I. A. Gorbunova, Sergei A. Shipilovskikh, Alexander S. Timin · 发表于:Biomaterials Science · 年份:2024 · DOI:10.1039/d4bm00390j · 被引用次数:14 · 研究领域:Synthesis and Characterization of Heterocyclic Compounds、Synthesis and Reactivity of Sulfur-Containing Compounds、Synthesis and biological activity
toxicity towards major organs such as heart, lung, liver, kidney, and spleen. Thus, this work provided an efficient strategy for the improved chemotherapy of solid tumors by using an encapsulated form of small molecule drugs.