Activation of the PPARγ/NF-κB pathway by A-MPDA@Fe 3 O 4 @PVP via scavenging reactive oxygen species to alleviate hepatic ischemia-reperfusion injury

作者：Dong Mo, Wei Cui, Linxin Chen, Juanjuan Meng, Yuting Sun, Kaiyong Cai, Jixi Zhang, Jianrong Zhang, Kui Wang, Xiaohe Luo · 发表于：Journal of Materials Chemistry B · 年份：2024 · DOI：10.1039/d4tb00423j · 被引用次数：10 · 研究领域：Advanced Nanomaterials in Catalysis、Nanoplatforms for cancer theranostics、Sulfur Compounds in Biology

@PVP can further protect liver tissue by activating the PPARγ/NF-κB pathway. This multiplex antioxidant enzyme therapy can provide new references for the treatment of IRI in organ transplantation and other ROS-related injuries such as fibrosis, cirrhosis, and bacterial and hepatic viral infection.