Optical coherence tomography (OCT) - versus angiography-guided strategy for percutaneous coronary intervention: a meta-analysis of randomized trials

作者：Yanwei Wang, Xi Yang, Yutao Wu, Yanqin Li, Yijiang Zhou · 发表于：BMC Cardiovascular Disorders · 年份：2024 · DOI：10.1186/s12872-024-03930-y · 被引用次数：5 · 研究领域：Coronary Interventions and Diagnostics、Optical Coherence Tomography Applications、Peripheral Artery Disease Management

Abstract Background Optical coherence tomography (OCT) guidance in percutaneous coronary intervention (PCI) has been shown to improve procedural outcomes. However, evidence supporting its superiority over angiography-guided PCI in terms of clinical outcomes is still emerging and limited. This study aimed to compare the efficacy and safety of OCT-guided PCI versus angiography‐guided PCI in patients with coronary artery disease (CAD). Methods A systematic search of electronic databases was conducted to identify randomized control trials (RCTs) comparing the clinical outcomes of OCT-guided and angiography‐guided PCI in patients with CAD. Clinical endpoints including all-cause mortality, myocardial infarction (MI), target lesion revascularization (TLR), stent thrombosis and major adverse cardiac events (MACE) were assessed. Results Eleven RCTs, comprising 2,699 patients in the OCT-guided group and 2,968 patients in the angiography-guided group met inclusion criteria. OCT-guided PCI was associated with significantly lower rates of cardiovascular death(RR 0.56; 95%CI: 0.32–0.98; p = 0.04; I 2 = 0%), stent thrombosis(RR 0.56; 95%CI: 0.33–0.95; p = 0.03; I 2 = 0%), and MACE (RR 0.79; 95%CI: 0.66–0.95; p = 0.01; I 2 = 5%). The incidence of all-cause death (RR 0.71; 95%CI: 0.49–1.02; p = 0.06; I 2 = 0%), myocardial infarction (RR 0.86; 95%CI: 0.67–1.10; p = 0.22; I 2 = 0%) and TLR (RR 0.98; 95%CI: 0.73–1.33; p = 0.91; I 2 = 0%) was non-significantly lower in the OCT-guided group. Concl...